Thanks to pfig, I'm now getting my mind blown by TIBCO's General Interface, which manages to shoehorn an entire, usable JavaScript-based IDE into a browser window.
The potential for this kind of thing is, well, amazing, and it makes me wonder whether all the Web 2.0 kiddies aren't just that - kids playing around with flashy UIs while the pros deliver usable tools.
But don't take my word for it: check out the screencasts .
And yes, the IDE works on Firefox for Mac OS X. For an enterprise environment, that's good enough for me.